East River BioSolutions’s proprietary TissueSpec™ technology enables the isolation of intact native extracellular matrix (ECM) directly from natural organs and tissues.
East River BioSolutions has produced extracellular matrix products from over 25 different organs, tissues, and tissue regions (nearly any organ or tissue of interest, including organ regions like renal cortex, medulla, and papilla), from healthy, diseased (e.g., tumor, fibrotic), and transgenic tissue sources.
With core expertise in the isolation, preservation, and processing of tissue-derived extracellular matrices, East River BioSolutions has developed a series of tissue- and disease- specific ECM products in multiple formats – including hydrogels, sponges, scaffolds, and solutions – for cell culture applications across life sciences and biomedical research.
Our TissueSpec™ products are derived from healthy porcine tissues (or alternatively from other species, including human tissues, in some cases). TissueSpec™ matrix products contain a suite of tissue-specific factors present in the native matrix (e.g., tissue-specific collagens, laminins, proteoglycans, matricryptic peptides, growth factors, and more) with no additional or exogenous factors, recreating the cell microenvironment or niche and providing the ideal physiologic substrate for in vitro cell-based research.